Multiobjective optimization for multiproduct batch plant

This work deals with the multicriteria cost–environment design of multiproduct batch plants, where the design variables are the size of the equipment items as well as the operating conditions. The case study is a multiproduct batch plant for the production of four recombinant proteins. Given the important combinatorial aspect of the problem, the approach used consists in coupling a

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Multiobjective optimization for multiproduct batch plant

Feb 15, 2006 · The framework for batch plant design proposed in this study integrates simple unit operation models into the batch plant wide model, which is then embedded in an outer optimization loop (see Fig. 3).The approach adopted in this work consists in coupling a stochastic algorithm, indeed a genetic algorithm (GA) with a discrete-event simulator (DES) (Dietz, Azzaro-Pantel, Pibouleau, & …

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Multiobjective optimization of multiproduct batch plants

Multiobjective optimization of multiproduct batch plants scheduling under environmental and economic concerns. "AICHE journal", Octubre 2011, vol. 57, núm. 10, p. 2766-2782.

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Optimal Design of Multiproduct Batch Plants under

Oct 27, 2008 · Abstract. In this study, we have introduced a fuzzy decision-making approach to design a multi-objective optimal design problem of a multiproduct batch chemical plant. The design of such plants necessary involves how equipment may be utilized, which means that plant scheduling and production must form an integral part of the design problem.

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Multi-objective process design in multi-purpose batch

Keywords: Batch process design; Multi-objective combinatorial optimization; Tabu Search; Multi-purpose plant 1. Introduction 1.1. Batch process design Speciality chemicals and pharmaceutical products are typ-ically produced in batch processes. Corresponding plants are often classified as multiproduct batch plants, in which every product

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Multiobjective Multiproduct Batch Plant Design Under

For this purpose, we extended a Multi-Objective Genetic Algorithm (MOGA) developed in previous works, taking into account simultaneously three criteria, i.e. minimization of the investment cost, the operation cost and the total production time. The case of study is a multiproduct batch plant for the production of proteins taken from the literature.

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Multiobjective optimization of multiproduct batch plants

Oct 22, 2010 · Multiobjective optimization of multiproduct batch plants scheduling under environmental and economic concerns Elisabet Capón-García, Dept. of Chemical Engineering, CEPIMA, Universitat Politècnica de Catalunya, ETSEIB, Av. Diagonal 647, Barcelona 08028, Spain

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Rule-Based Scheduling of Single-Stage Multiproduct Batch

Jun 07, 2012 · A new rule-based model for single-stage multiproduct scheduling problem (SMSP) in batch plants with parallel units is proposed. The scheduling problem is decomposed into two subproblems of order assignment and order sequencing. A group of order assignment rules are introduced to select suitable units for customer orders. While flexible constraint handling strategies …

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Optimal Solutions of Multiproduct Batch Chemical Process

Optimal design problem are widely known by their multiple performance measures that are often competing with each other. In this paper, an optimal multiproduct batch chemical plant design is presented. The design is firstly formulated as a multiobjective optimization problem, to be solved using the well suited non dominating sorting genetic algorithm (NSGA-II).

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Multiobjective Multiproduct Batch Plant Design Under

Dietz, Adrian and Aguilar-Lasserre, Alberto and Azzaro-Pantel, Catherine and Pibouleau, Luc and Domenech, Serge Multiobjective Multiproduct Batch Plant Design Under Uncertainty. (2006) In: 16th European Symposium on Computer Aided Process Engineering (ESCAPE 16) and 9th International Symposium on Process Systems Engineering, 17-19 July 2006, Garmisch PartenKirschen, Allemagne .

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Process performance models in the optimization of

In this work we propose a model that simultaneously optimizes the process variables and the structure of a multiproduct batch plant for the production of recombinant proteins. The complete model includes process performance models for the unit stages and a posynomial representation for the multiprod …

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Optimization of a biotechnological multiproduct batch

Optimization of a biotechnological multiproduct batch plant design for the manufacture of four different products: A real case scenario Gabriela Sandoval Centre of Biotechnology and Bioengineering, CeBiB, Department of Chemical Engineering and Biotechnology, University of …

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Optimization of a biotechnological multiproduct batch

Optimization of a biotechnological multiproduct batch plant design for the manufacture of four different products: A real case scenario Gabriela Sandoval Centre of Biotechnology and Bioengineering, CeBiB, Department of Chemical Engineering and Biotechnology, University of …

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MULTICRITERIA OPTIMIZATION OF MULTIPRODUCT BATCH …

Dec 01, 2010 · multicriteria optimization of multiproduct batch chemical process using genetic algorithm In this paper, an optimal multiproduct batch chemical plant design is presented. The design is first formulated as a multiobjective optimization problem, to be solved using the well‐suited nondominating sorting genetic algorithm (NSGA‐II).

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Multi-objective process design in multi-purpose batch

Apr 15, 2004 · 1. Introduction1.1.. Batch process designSpeciality chemicals and pharmaceutical products are typically produced in batch processes. Corresponding plants are often classified as multiproduct batch plants, in which every product follows the same sequence through all the process steps, or as multi-purpose batch plants, in which each product follows its own distinct processing …

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Optimal Reliable Retrofit Design of Multiproduct Batch Plants

Mar 19, 2004 · The problem of the retrofit design of a multiproduct batch plant is considered from a new perspective that involves explicit consideration of inherent reliability and maintainability characteristics of existing and new equipment. Until now, in multiproduct batch plant retrofitting formulations, the production capacity has been specified by the limiting batch size and limiting cycle time. We

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Multiobjective optimization of multiproduct batch plants

Oct 01, 2011 · Read "Multiobjective optimization of multiproduct batch plants scheduling under environmental and economic concerns, Aiche Journal" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

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Scheduling of a Multiproduct Dairy Programming

Multiproduct multistage batch plants are commonly used in the produc-tion of end products in the chemical, pharmaceutical, and food processing industries. In such plants, di erent products are produced with common equipment and shared resources. As discussed in Hazaras et al. (2013), the

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Efficient short-term scheduling of multiproduct batch

Apr 10, 2008 · In this paper, a novel formulation for the short-term scheduling of multiproduct batch plants under demand uncertainty is presented. Then it is solved…

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Multiobjective Optimization of Multiproduct Batch Plants

Recently, Capón-García et al. (2011) proposed a multiobjective optimization model for the multiproduct batch plant scheduling, which simultaneously takes into account the environmental and

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